Endocrine Abstracts

Introduction: Insulinoma is a rare, generally benign neuroendocrine tumor, primarily manifesting as hypoglycemia in non-diabetic patients. Although surgery is the gold standard treatment for insulinoma, managing hypoglycemia becomes challenging in cases where surgery is not feasible. This challenge arises due to significant side effects that often limit the use of most drugs and therapeutic alternatives.Case report: A 90-year-old non-diabetic man was adm...

Aim: Obesity was shown to be related to global cognitive decline, being especially altered the executive function and the information processing speed. Bariatric surgery (BS) is an effective means of weight reduction in severely obese patients and correlates with improvements in neurocognition. The mechanisms underlying these improvements are not fully elucidated.Material and Methods: Prospective, observational study, including consecutive patients that ...

Introduction: Familial non-medullary thyroid cancer(FNMTC) represents 3–9% of thyroid cancer cases. Although the susceptibility genes for syndromic FNMTC are known, most cases of FNMTC are nonsyndromic and the genetic causes are unknown.Patients and methods: We conducted a multicenter study to identify a candidate susceptibility gene for nonsyndromic FNTMC. We collected blood specimens, clinical and pathological data from 38 kindreds with FNMTC (32 ...

Most thyroid nodules are benign and majority do not require treatment, except for those large nodules that cause symptoms (compression, hormonal dysfunction and/or esthetic problems). Microwave ablation (MWA) is an attractive therapeutic option because it is minimally invasive, relatively inexpensive, capable of providing coagulative necrosis, and has a short treatment time. In the following, we present the experience of our hospital.Objective: To evalua...

Aim: Bariatric surgery (BS) modifies body composition. The aim of the study was to establish the first step toward the introduction of the ultrasound (US) and bioelectrical impedance analysis (BIA) in the evaluation of body composition before and after BS. In addition, as obesity was shown to be related to global cognitive decline, we aim to determine possible changes in cognitive test before and after BS.Material and Methods: a prospective pilot study o...

Aim: Gestational diabetes (GDM) has been associated with an increased risk ofneurocognitive outcomes in offspring such as attention deficit/hyperactive disorders (ADHD) and autism spectrum disorders (ASD). However GDM-related comorbidities (obesity or excessive weight gain –EWG-) in this setting have been scarcely studied. So, the aim of our study was to estimate the risk of ADHD and ASD in this population.Material and Methods: Cohort study. Single...

AimObesity was shown to be related to global cognitive decline, being especially altered the executive function and the information processing speed. Additionally, sarcopenic obesity (SO) was associated independently with a deterioration in global cognition, executive function, information processing speed, global memory and cerebral atrophy in patients > 65 years. However, at present there is no data regarding the role of sarcopenia in the cognitive...

Objectives: Most transgender persons (0.3-0.5% of total population) are under gender-affirming hormone therapy (GAHT). Several studies have reported an increased morbimortality due to cardiovascular events (CVE), infectious disease and suicide. However, these studies were made on small populations and short follow up. We evaluated the changes on anthropometric variables, risk factors for cardiovascular diseases (CVD) and CVE at 5 and 10 years of follow up in a transgender popu...